Rx
Notes
In emergency
Disease annotations
Rx
- Amoxicillin 500 mg capsule 1x2x10-14 or 250 mg capsule 1x3x10-14
- Revenin 500mg tablets 1x 4 up to 2 x 4 until fever subside
- Gurgle with salt and water solution (don’t swallow it ) 3 times daily
- Soft food and warm drinks
Notes
Amoxicillin :
Dosage Forms & Strengths
1000mg, 1g, 500mg, 750mg 625mg tablets, 500mg, 250mg capsules, 375mg/5ml suspension ,250mg/5ml suspension, 125mg/5ml suspension
Trade names:
Amoxil, Moxiram, Penamox, Ultramox, Moxilen, Hymox, Amoxapen, Julphamox, Ospamox, Amoxydar, Amoxibel
Therapeutic indication and dose :
Ear, Nose, & Throat Infections
Mild to moderate infections
500 mg PO q12hr or 250 mg PO q8hr for 10-14 days
Severe infections
500 mg PO q8hr for 10-14 days
Genitourinary Tract Infections
Mild to moderate infections
500 mg PO q12hr or 250 mg PO q8hr
Severe infections
500 mg PO q8hr
Skin & Skin Structure Infections
Mild to moderate infections
500 mg PO q12hr or 250 mg PO q8hr
Severe infections
500 mg PO q8hr
Lower Respiratory Tract Infections
500 mg PO q8hr for 10-14 days
Helicobacter Pylori
H pylori infection and active or 1-year history of duodenal ulcer
Triple therapy
1 g PO q12hr for 14 days with lansoprazole (30 mg) and clarithromycin (500 mg)
Dual therapy
1 g PO q8hr for 14 days with lansoprazole (30 mg) in patients intolerant of, or resistant to, clarithromycin
Infective Endocarditis
Prophylaxis
2 g PO 30-60 min before procedure
Chlamydial Infection in Pregnant Women
First trimester: 500 mg PO q8hr for 7 days
Contraindications:
Hypersensitivity to penicillin’s, semi-synthetic penicillin’s or cephalosporin.
Liver problems
Renal impairment
Pregnancy:
Category B
Breastfeeding :
Amoxicillin is excreted into breast milk in small quantities
Diarrhea and fungus infection of the mucous membranes are possible in the breast-fed infant, so that breast-feeding might have to be discontinued.
Common side effects:
Anaphylaxis
Anemia
AST/ALT elevation
Mucocutaneous candidiasis
Diarrhea
Headache
Nausea
Vomiting
Rash
Pseudomembranous colitis
Paractamol
Analgesic and antipyretics
Not anti-inflammatory effect
Suitable for Temperature between (37.5C – 38.5C)
Safe under 6 months
Trade names : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )
Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories, 1g/100ml solution for infusion
Dose :
Tablet, capsule :
500mg tabs 1-2 tabs /cap every 6 hours
Syrup, suspension :
< 5year : 125mg/5ml susp (w/2) Every 4 – 6 hours
5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours
Suppositories :
<1Y : 125 mg supp Every 8 hours (1 supp x 3 )
>1Y : 250mg supp Every 8 hours ( 1supp x 3 )
Iv solution 1g/100ml :
<10kg : 0 .75ml/kg
>10kg , <50kg : 1.5ml/kg
>50kg : 100ml Slowly over 15 minute
Maximum dose : 4g daily
Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding
In emergency
In Emergency room:
- Give antipyretic:
- Perflgan 1g/100ml intravenous injection :
Dose:
Pediatrics:
- < 10kg : 0 .75ml/kg
- >10kg , <50kg : 1.5ml/kg
- >50kg : 100ml Slowly over 15 minute
Adult:
- 100ml Slowly over 15 minute
OR
- Diclofenac sodium injection 75 mg/3ml intramuscular injection :
Dose:
Pediatrics:
- > 1year : 1ml/20kg every 12 hour .
Adult:
- 25 to 75 mg(1-3ml) depending on the severity pain.
- If the pain still severe, you may decide to give a second injection after 6 hours.
- Give Antibiotic:
- Lincomycin 600mg/2ml
Dose:
Pediatrics:
- IV: 10-20 mg/kg/day divided q8-12hr
- IM: 10 mg/kg q12-24hr
Adult:
- IM: 600 mg q12-24hr
- IV: 600-1000 mg q8-12hr; not to exceed 8 g/day
Disease annotations