- Amoclan 625mg tablet 1 x 3 x 10 Or Amoclan 1g tablet 1 x 2 x 10
- Voltaren 75mg tablet 1 x 2 until fever subside
- Gurgle with salt and water solution (don’t swallow it ) 3 times daily
- Soft food and warm drinks
Amoxicillin with clavulanic acid
Dosage Forms & Strengths:
- 375mg tablet, 625mg tablet, 1g tablet, 156mg/5ml suspension, 312mg /5ml suspension, 200mg/5ml suspension, 400mg/5ml suspension, 600mg/5ml suspension, 457 mg /5ml suspension, 62.5mg/5ml drops , 600 vial injection , 1200 vial injection .
Trade names :
- Clavar , Klavox, Moxiclav, Ramoclav, Curam, Julmentin, Augmentin, Clavodar, Amoclan
Therapeutic indication and dose :
Lower Respiratory Tract Infection :
- Mild to moderate: 375mg PO q8hr for 10 days
- Severe: 625 mg PO q8hr or 2000 mg (2 extended-release tabs) PO q12hr for 7-10 days
Chronic Obstructive Pulmonary Disease
- 625 mg PO q8hr
Acute Bacterial Sinusitis
- 2000 mg (2 extended-release tablets) PO q12hr for 10 days
Animal/Human Bite Wounds
- 625mg PO q8hr for 3-5 days
Erysipelas
- 625 mg PO q8hr for 7-10 days
Pyelonephritis
- 625mg PO q8hr
Skin Abscess
- 625 mg PO q12hr
Diabetic Foot
Mild to moderate, localized cellulitis
- 2000 mg (2 extended-release tablets) PO q12hr for 7-14 days
Group A Streptococci, Chronic Carrier
- 40 mg/kg/day PO divided q8hr for 10 days; not to exceed 2000 mg/day
Contraindications:
- Hypersensitivity to penicillin’s
- History of a severe immediate hypersensitivity reaction (e. g. Anaphylaxis) to another beta-lactam agent (e. g. A cephalosporin, carbapenem or monobactam).
- Hepatic and renal impairment
Pregnancy:
- Category B
Breastfeeding :
- Both substances are excreted into breast milk, diarrhea and fungus infection of the mucous membranes are possible in the breast-fed infant, so that breast-feeding might have to be discontinued.
Common side effects:
- Diarrhea, nausea and vomiting.
- Mucocutaneous candidosis
- Skin rash, itching, hives
- Vaginal itching and discharge
Diclofenac sodium
- Mainly analgesic
- Has anti-inflammatory effect
- Suitable for temperature >39
- Contraindicated in < 1year age
- After meal
Trade names of diclofenac : (Diclogesic, Votrex, Infla-ban, Voltaren, Tratul, Rofenac Diclofen, Olfen,Optifen, Almiral, Clofen, Diclosal, Divido, Diclomax, Nalgofen, Difen,)
Other concentrations: 12.5 mg, 50, 100 suppositories, 25, 50, 100 tablet, 100 capsules, 75 mg/3ml mg injection
Dose :
Tablet:
- 75 mg to 150 mg daily in two or three divided doses.
Suppositories :
Adults: 75-150mg daily, in divided doses every 12 hour
children:
- 1-3 years or <15 kg: 12.5 mg suppositories every 12 hour
- 3-12years or >15kg : 25mg suppositories every 12 hour
IM Injection 75mg/3ml
Adults : 25 to 75 mg depending on the severity pain.
The maximum daily dose is :150 mg.
Contraindication:
- History of hypersensitivity to diclofenac sodium
- Asthma
- Hypertension
- current or recent stomach ulcer
- severe heart failure.or evere liver disease
Pregnancy : not usually recommended in pregnancy
Give antipyretic:
Perflgan 1g/100ml intravenous injection :
Dose:
Pediatrics:
<10kg : 0 .75ml/kg
>10kg , <50kg : 1.5ml/kg
>50kg : 100ml Slowly over 15 minute
Adult:
100ml Slowly over 15 minute
OR
Diclofenac sodium injection 75 mg/3ml intramuscular injection :
Dose:
Pediatrics:
> 1year : 1ml/20kg every 12 hour .
Adult:
25 to 75 mg(1-3ml) depending on the severity pain.
If the pain still severe, you may decide to give a second injection after 6 hours.
Give Antibiotic:
Lincomycin 600mg/2ml
Dose:
Pediatrics:
IV: 10-20 mg/kg/day divided q8-12hr
IM: 10 mg/kg q12-24hr
Adult:
IM: 600 mg q12-24hr
IV: 600-1000 mg q8-12hr; not to exceed 8 g/day