1. Azithromycin 500mg capsule  on first day then 250mg capsules orally 1×1 on Days 2-5
2. Ibugesic 400mg tablet 1 x 3 until fever subside
3. Gurgle with salt and water solution (don’t swallow it ) 3 times daily
4. Soft food and warm drinks

Azithromycin

Dosage Forms & Strengths:

• 250mg ,500mg  capsule and tablet, 500mg vial, 200mg/5ml suspension, 300mg /7.5ml suspension

Trade names  :

Zocin, Zimax , Zomax, Azomycin, Azi_once, Zithromax, Azitam, Zithrova, Zaha, Zilacid, Azicure, Azomyne , Azox

Therapeutic indication and dose :

Community-acquired Pneumonia

• 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5

Pharyngitis or Tonsillitis

• 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5

Uncomplicated skin/skin structure

• 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5

Acute bacterial exacerbations of chronic obstructive pulmonary disease

• 500 mg PO qDay for 3 days OR
• 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5

Acute bacterial sinusitis

• 500 mg PO qDay x 3 days

Genital Ulcer Disease (Chancroid)

• 1000 mg PO x 1 dose

Nongonococcal or Gonococcal Urethritis and Cervicitis

• 1000 mg PO x 1 dose

Cat Scratch Disease (Off-label)

• >45.5 kg: 500 mg PO once, then 250 mg once daily for 4 days

Pertussis (Off-label)

• 500 mg PO once, then 250 mg once daily for 4 days

Endocarditis (Off-label)

Prophylaxis

• 500 mg PO 30-60 min before procedure

Contraindications:

• Hypersensitivity to azithromycin, erythromycin, any macrolide

Pregnancy:

• The safety of azithromycin has not been confirmed with regard to the use of the active substance during pregnancy. Therefore, Azithromycin should only be used during pregnancy if the benefit outweighs the risk

Breastfeeding :

• Azithromycin has been reported to be secreted into human breast milk
• Because it is not known whether azithromycin may have adverse effects on the breast-fed infant, nursing should be discontinued during treatment with Azithromycin. Among other things diarrhea, fungus infection of the mucous membrane is possible in the nursed infant. It is recommended to discard the milk during treatment and up until 2 days after discontinuation of treatment. Nursing may be resumed thereafter. 

Common side effects:

• Anorexia
• Dizziness, headache, paranesthesia, dysgeusia
• Visual impairment, Deafness
• Vomiting, dyspepsia
• Rash, pruritus

Diclofenac sodium

• Mainly analgesic
• Has anti-inflammatory effect
• Suitable for temperature >39
• Contraindicated in < 1year age
• After meal

Trade names  of diclofenac  : (Diclogesic, Votrex, Infla-ban, Voltaren, Tratul, Rofenac Diclofen, Olfen,Optifen, Almiral, Clofen, Diclosal, Divido, Diclomax, Nalgofen, Difen,)

Other concentrations: 12.5 mg, 50, 100 suppositories, 25, 50, 100 tablet, 100 capsules, 75 mg/3ml mg injection

Dose : 

Tablet: 

• 75 mg to 150 mg daily in two or three divided doses. 

Suppositories :

Adults: 75-150mg daily, in divided doses every 12 hour

children:

• 1-3 years or <15 kg: 12.5 mg suppositories every 12 hour
• 3-12years or >15kg : 25mg suppositories every 12 hour

IM Injection 75mg/3ml

Adults :  25 to 75 mg depending on the severity pain. 

The maximum daily dose is :150 mg.

Contraindication: 

• History of hypersensitivity to diclofenac sodium
• Asthma 
• Hypertension
• current or recent stomach ulcer
• severe heart failure.or evere liver disease

Pregnancy : not usually recommended in pregnancy