- Erythrodar 400mg tablet orally every 6 hours
- Voltaren 75mg tablet 1 x 2 until fever subside
- Gurgle with salt and water solution (don’t swallow it ) 3 times daily
- Soft food and warm drinks
Erythromycin
Dosage Forms & Strengths:
250mg tablet , 400mg tablet , ,200mg tablet , 200mg/5ml suspension
Trade names :
Rythromac ,Erythrodar
Therapeutic indication and dose :
General Dosing Recommendations
- 400 mg PO q6hr or
- 250-500 mg PO q6-12hr or 500 mg q12hr or 333 mg PO q8hr
- Severe infections: Up to 4 g/day
Intestinal amebiasis
- 400 mg PO q6hr for 10-14 days
Legionnaire Disease
- 400-1000 mg PO q6hr for 21 days
Pertussis
- 500 mg PO q6hr for 14 days
Streptococcal infections
- 400 mg PO divided q12hr for 10 days
Urethritis
- 800 mg PO q8hr for 7 days or
- 500 mg PO q6hr for 7 days
Lymphogranuloma Venereum
- 500 mg PO q6hr for 21 days
Contraindications:
- Known hypersensitivity to erythromycin.
- Erythromycin is contraindicated in patients taking simvastatin
Pregnancy and lactation:
- Observational studies in humans have reported cardiovascular malformations after exposure to medicinal products containing erythromycin during early pregnancy.
- Erythromycin has been reported to cross the placental barrier in humans, but foetal plasma levels are generally low.
- There have been reports that maternal macrolide antibiotics exposure within 7 weeks of delivery may be associated with a higher risk of infantile hypertrophic pyloric stenosis (IHPS).
- Erythromycin can be excreted into breast-milk. Caution should be exercised when administering erythromycin to lactating mothers
Side effect:
- Upper abdominal discomfort, nausea, vomiting, diarrhea
- Pancreatitis, anorexia, infantile hypertrophic pyloric stenosis.
- Allergic reactions ranging from urticaria and mild skin eruptions to anaphylaxis
Deafness, tinnitus
Diclofenac sodium
- Mainly analgesic
- Has anti-inflammatory effect
- Suitable for temperature >39
- Contraindicated in < 1year age
- After meal
Trade names of diclofenac : (Diclogesic, Votrex, Infla-ban, Voltaren, Tratul, Rofenac Diclofen, Olfen,Optifen, Almiral, Clofen, Diclosal, Divido, Diclomax, Nalgofen, Difen,)
Other concentrations: 12.5 mg, 50, 100 suppositories, 25, 50, 100 tablet, 100 capsules, 75 mg/3ml mg injection
Dose :
Tablet:
- 75 mg to 150 mg daily in two or three divided doses.
Suppositories :
Adults: 75-150mg daily, in divided doses every 12 hour
children:
- 1-3 years or <15 kg: 12.5 mg suppositories every 12 hour
- 3-12years or >15kg : 25mg suppositories every 12 hour
IM Injection 75mg/3ml
Adults : 25 to 75 mg depending on the severity pain.
The maximum daily dose is :150 mg.
Contraindication:
- History of hypersensitivity to diclofenac sodium
- Asthma
- Hypertension
- current or recent stomach ulcer
- severe heart failure.or evere liver disease
Pregnancy : not usually recommended in pregnancy
Give antipyretic:
Perflgan 1g/100ml intravenous injection :
Dose:
Pediatrics:
<10kg : 0 .75ml/kg
>10kg , <50kg : 1.5ml/kg
>50kg : 100ml Slowly over 15 minute
Adult:
100ml Slowly over 15 minute
OR
Diclofenac sodium injection 75 mg/3ml intramuscular injection :
Dose:
Pediatrics:
> 1year : 1ml/20kg every 12 hour .
Adult:
25 to 75 mg(1-3ml) depending on the severity pain.
If the pain still severe, you may decide to give a second injection after 6 hours.
Give Antibiotic:
Lincomycin 600mg/2ml
Dose:
Pediatrics:
IV: 10-20 mg/kg/day divided q8-12hr
IM: 10 mg/kg q12-24hr
Adult:
IM: 600 mg q12-24hr
IV: 600-1000 mg q8-12hr; not to exceed 8 g/day