1. Avoid exposure to allergen
2. In excessive nasal secretions (Rinorrhea,sneezing,itching):

• Fenistil drop 1mg/1ml ( 2 drops/kg/day divided into 3 doses)

3. In nasal obstruction:

• Apisal 9mg/ml drop 1drop 4-6 times daily

Dimetindene

Available forms:

• Fenistil:  drop 1mg/1ml, 4mgcaps, 1mgtab
• Pedia fast: drop 0.1g/100ml, 0.01g/100ml syrup
• Alergin:  drop 1mg/1ml (1 ml = 20 drops).
• Fencil:  drop 1mg/1ml
• 1 ml contains dimetindene maleate 1 mg (1 ml = 20 drops).

 Therapeutic indications

• Symptomatic treatment of allergic diseases:
• Skin: Urticaria, pruritus of various etiology, endogenous eczema with previous medical diagnosis.
• Respiratory system: Seasonal (hay fever) and perennial rhinitis with previous medical diagnosis.
• Relieve of itching associated with infectious diseases (e.g. chickenpox) with previous medical diagnosis or after an insect bite or stings.

Dose:

1mg/1ml oral drops, 0.1g/100ml drop:

• Adults :The recommended daily dose is 3 – 6 mg of dimetindene maleate divided into 3 doses, 
• 20 –40 drops 3× a day.
• Paediatric  The recommended daily dose for children 1 – 11 years is 0.1 mg dimetindene maleate/kg body
• 2 drops/kg/day divided into 3 doses.

1mg tablet:

• 1 to 2 milligrams three times daily 

0.01g/100ml syrup:

• the recommended dose is 1 teaspoonful (5 ml) of a 0.01g/100ml syrup 3-4 times daily

4mg capsule :

• 1capsule once  daily 

Contraindications :

• Hypersensitivity to the active substance or to any of the excipientsInfants and children under 1 year of age.

pregnancy and lactation :

• Pregnancy There are no data about the use of dimetindene maleate during pregnancy. 
• Dimetindene maleate should not be used in pregnant women unless the benefit of treating the mother outweighs the risk for the foetus

Breast-feeding :

• There is a well-founded presumption that dimetindene can be excreted in human milk. So its not recommended.

Side effect :

• Fatigue
• Somnolence, nervousness

Apisal 9mg/ml drop, 7.4mg/ml spray

• Nasal decongestant
• is a safe drug-free physiological saline solution
• can be used as often as needed, to cleanse and moisturize nasal passages and help in removing incrustations, bacteria, viruses, allergens or irritants entrapped in the nasal mucosa.
• Nasal Dryness & Congestion
• relieves nasal congestion by thinning mucus and moisturizes membranes

Dose in adult and pediatrics:

• 1puffs /drop 4-6 times daily

Pregnancy and lactation:

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