1. Levofloxacin 500mg capsules orally  1x1x10-14 or 750mg 1x1x5
2. dolocet 500mg tablets 1x 4 up to 2 x 4 until fever subside

If there are excessive secretions and sneezing   add:

• Dimetindene 4mg caps 1caps every 4-6 hours

 If there is nasal obstruction add :

• Decozal 0.1% spray/drop 2-3 drops in each nostrils up to 3 times daily up to 7 days

Levofloxacin 

Dosage Forms & Strengths

• 250mg tablet ,500mg tablet, 750mg tablet , 500mg/100ml, 250mg/50ml, 5mg/ml for iv infusion

Trade names  :

• Tavanic , Avoxin, Joswe avoxin , Levotop, Avicare, levanix, Levaquin, Zynolev, Loxacin, Matador, Uniflox, Evomax, joxevo, Tavaquin, Lefort, levoflox, Levonic, Talerin, Ravivo, Nevotic, Loxamox .

Therapeutic indication and dose :

Community-Acquired Pneumonia

• 500 mg PO/IV once daily for 7-14 days or 750 mg PO/IV once daily for 5 days

Nosocomial Pneumonia

• 750 mg PO/IV once daily for 7-14 days

Acute Bacterial Sinusitis

• 500 mg PO/IV once daily for 10-14 days or 750 mg PO/IV once daily for 5 days

Acute Bacterial Exacerbation of Chronic Bronchitis

• 500 mg PO/IV once daily for ≥7 days

Skin/Skin Structure Infections

• Uncomplicated: 500 mg PO/IV once daily for 7-10 days
• Complicated: 750 mg PO/IV once daily for 7-14 days

Chronic Bacterial Prostatitis

• 500 mg PO/IV once daily for 28 days

Complicated Urinary Tract Infections & Acute Pyelonephritis

• 250 mg PO/IV once daily for 10 days or 750 mg PO/IV once daily for 5 days

Uncomplicated Urinary Tract Infections

• 250 mg PO/IV once daily for 3 days

Limitations-of-use: Reserve fluoroquinolones for patients who do not have other available treatment options for uncomplicated urinary tract infections

• 500 mg PO/IV once daily for 10-14 days

Acne Vulgaris (Off-label)

• 100 mg PO q8hr for 4 weeks

Epididymitis (Off-label)

• 500 mg PO qDay for 10 days

Contraindications

• Hypersensitive to levofloxacin or other quinolones
• Patients with epilepsy
• History of tendon disorders related to fluoroquinolone administration
• In children or growing adolescents
• During pregnancy
• In breast-feeding women

Side effect:

• Headache, Dizziness
• Vomiting, Nausea, Diarrhea
• Insomnia

Paractamol

• Analgesic and antipyretics
• Not anti-inflammatory effect
• Suitable for Temperature between (37.5C – 38.5C)
• Safe under 6 months

Trade names  : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )

Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories,1g/100ml solution for infusion

Dose : 

Tablet, capsule : 

• 500mg tabs 1-2 tabs /cap every 6 hours

Syrup, suspension :

• < 5year  : 125mg/5ml susp (w/2) Every 4 – 6 hours
• 5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours 

Suppositories :

• <1Y : 125 mg supp Every 8 hours  (1 supp x 3 )
• >1Y : 250mg supp Every 8 hours ( 1supp x 3 )

Iv solution 1g/100ml :

• <10kg : 0 .75ml/kg 
• >10kg , <50kg :  1.5ml/kg
• >50kg : 100ml Slowly over 15 minute
  • Skin: Urticaria, pruritus of various etiology, endogenous eczema with previous medical diagnosis.
  • Respiratory system: Seasonal (hay fever) and perennial rhinitis with previous medical diagnosis.

Maximum dose : 4g daily 

Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding 

Dimetindene

Available forms:

• Fenistil:  drop 1mg/1ml, 4mgcaps, 1mgtab
• Pedia fast: drop 0.1g/100ml, 0.01g/100ml syrup
• Alergin:  drop 1mg/1ml (1 ml = 20 drops).
• Fencil:  drop 1mg/1ml
• 1 ml contains dimetindene maleate 1 mg (1 ml = 20 drops).

 Therapeutic indications

• Symptomatic treatment of allergic diseases:
• Relieve of itching associated with infectious diseases (e.g. chickenpox) with previous medical diagnosis or after an insect bite or stings.

Dose:

1mg/1ml oral drops, 0.1g/100ml drop:

• Adults :The recommended daily dose is 3 – 6 mg of dimetindene maleate divided into 3 doses, 
• 20 –40 drops 3× a day.
• Paediatric  The recommended daily dose for children 1 – 11 years is 0.1 mg dimetindene maleate/kg body
• 2 drops/kg/day divided into 3 doses.

1mg tablet:

• 1 to 2 milligrams three times daily 

0.01g/100ml syrup:

• the recommended dose is 1 teaspoonful (5 ml) of a 0.01g/100ml syrup 3-4 times daily

4mg capsule :

• 1capsule once  daily 

Contraindications :

• Hypersensitivity to the active substance or to any of the excipientsInfants and children under 1 year of age.

pregnancy and lactation :

• Pregnancy There are no data about the use of dimetindene maleate during pregnancy. 
• Dimetindene maleate should not be used in pregnant women unless the benefit of treating the mother outweighs the risk for the foetus

Breast-feeding :

• There is a well-founded presumption that dimetindene can be excreted in human milk. So its not recommended.

Side effect :

• Fatigue
• Somnolence, nervousness

Otrivine

Otrivine Nasal Spray contains the active ingredient xylometazoline hydrochloride which helps to open up and clear the nasal passages by reducing the excessive nasal secretions and returning the swollen blood vessels to their normal size.

 Used in :

• nasal congestion (blocked nose, including colds)
• allergic rhinitis
• sinusitis.
• Not used>5 days Cause rebound congestion

Pregnancy : not  recommended

Available forms:

• Otrivin 0.1% spray/drop , .05% spray /drop
• Decozal 0.1% spray/drop , .05% spray /drop
• Xylomet 0.1% spray

Dose:

Adult

• 0.1% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child>6y

• 0.05% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child 6months-6y

• 0.05% Nasal drop 1drops in each nostrils up to 3 times daily