Moxifloxacin 400 mg tablet 1×1 x5-10 days

2. dolocet 500mg tablets 1x 4 up to 2 x 4 until fever subside

If there are excessive secretions and sneezing   add:

• Anallerge 4mg tab 1tab every 4-6 hours

 If there is nasal obstruction add :

• Otrivin 0.1% spray/drop 2-3 drops in each nostrils up to 3 times daily not more than 7 days

Moxifloxacin

Dosage Forms & Strengths

• 400mg tablet, 436.8 mg tab ,400mg/250ml solution for injection, 5mg /ml solution for injection , 1.6mg/ml solution for injection

Trade names  :

• Muxava, Avaquin,Avalox, AVORES JPM, Vigamox, Elevemox , Mofloxine , Moxiquin

Therapeutic indication and dose :

Acute Bacterial Sinusitis

• 400 mg PO/IV qDay for 5-10 days

Community-Acquired Pneumonia

• 400 mg PO/IV qDay for 7-14 days

Acute Exacerbation of Chronic Bronchitis

• Indicated for acute exacerbations of chronic bronchitis caused by bacterial infections
• 400 mg PO/IV qDay for 5 days

Skin & Skin Structure Infections

• Uncomplicated: 400 mg PO/IV qDay for 7 days
• Complicated: 400 mg PO/IV qDay for 7-21 days

Intra-abdominal Infections

• Complicated: 400 mg PO/IV qDay for 5-14 days

Pneumonic & Septicemic Plague

• Indicated in adults for the treatment of plague, including pneumonic and septicemic plague, caused by susceptible isolates of Yersinia pestis; it is also indicated for prophylaxis of plague in adults
• 400 mg PO/IV qDay x10-14 days
• Begin administration as soon as possible after suspected or confirmed exposure to Yersinia pestis

Contraindications

• Hypersensitivity to moxifloxacin, other quinolones
• Pregnancy and lactation
• Patients below 18 years of age. 
• Patients with a history of tendon disease/disorder related to quinolone treatment. 

Side effects:

• Headache
• Dizziness
• Nausea, Vomiting, Diarrhea
• Gastrointestinal and abdominal pains

Paractamol

• Analgesic and antipyretics
• Not anti-inflammatory effect
• Suitable for Temperature between (37.5C – 38.5C)
• Safe under 6 months

Trade names  : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )

Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories,1g/100ml solution for infusion

Dose : 

Tablet, capsule : 

• 500mg tabs 1-2 tabs /cap every 6 hours

Syrup, suspension :

• < 5year  : 125mg/5ml susp (w/2) Every 4 – 6 hours
• 5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours 

Suppositories :

• <1Y : 125 mg supp Every 8 hours  (1 supp x 3 )
• >1Y : 250mg supp Every 8 hours ( 1supp x 3 )

Iv solution 1g/100ml :

• <10kg : 0 .75ml/kg 
• >10kg , <50kg :  1.5ml/kg
• >50kg : 100ml Slowly over 15 minute

Maximum dose : 4g daily 

Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding 

Chlorpheniramine

Available forms:

• Allerfin: 4mg tab, 10mg/ml ampule, 2.5mg/5ml syrup
• Anallerge: 4mg tab 2mg/5ml syrup
• Chlorohistol:  4mg tab

 Therapeutic indications:

• symptomatic control of all allergic conditions responsive to antihistamines, including hay fever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergy, drug and serum reactions, insect bites.
• Also indicated for the symptomatic relief of itch associated with chickenpox.

Method of administration:

• Adults:  4 mg (1 tablet or 10 ml) every 4-6 hours. Not more than six doses (24 mg) a day if under 65 years of age, or more than a total of three doses (12 mg) a day if over 65 years.
• Children aged 6-11 years: 2 mg (5 ml) every 4-6 hours. Not more than a total of six doses (12 mg) a day.
• Children aged 2-5 years: 1 mg (2.5 ml liquid medicine) every 4-6 hours. Not  more than a total of six doses (6 mg) a day.
• Children 1 year-23 months: 1 mg (2.5 ml liquid medicine) twice daily, preferably morning and evening

Contraindications

• contra-indicated in patients who are hypersensitive to antihistamines or to any of the tablet ingredients.

Pregnancy

• There are no adequate data from the use of chlorphenamine maleate in pregnant women. The potential risk for humans is unknown. Use during the third trimester may result in reactions in the newborn or premature neonates. Not to be used during pregnancy unless considered essentially by a physician.

Lactation

• Chlorphenamine maleate and other antihistamine may inhibit lactation and may be secreted in breast milk. Not to be used during lactation unless considered essential by a physician

Side effects :

• Sedation
• drowsiness, dizziness, blurred vision and psychomotor impairment
• Nausea, dry mouth
• Disturbance in attention

Otrivine

Otrivine Nasal Spray contains the active ingredient xylometazoline hydrochloride which helps to open up and clear the nasal passages by reducing the excessive nasal secretions and returning the swollen blood vessels to their normal size.

 Used in :

• nasal congestion (blocked nose, including colds)
• allergic rhinitis
• sinusitis.
• Not used>5 days Cause rebound congestion

Pregnancy : not  recommended

Available forms:

• Otrivin 0.1% spray/drop , .05% spray /drop
• Decozal 0.1% spray/drop , .05% spray /drop
• Xylomet 0.1% spray

Dose:

Adult

• 0.1% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child>6y

• 0.05% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child 6months-6y

• 0.05% Nasal drop 1drops in each nostrils up to 3 times daily