1. Ciprofloxacin 500 mg tablet 1×2 x10 days
2. Dolocet 500mg tablets 1x 4 up to 2 x 4 until fever subside

If there are excessive secretions and sneezing   add:

• Histal 10mg orally once a day

 If there is nasal obstruction add :

• Xylomet 0.1% spray/drop 2-3 drops in each nostrils up to 3 times daily not more than 7 days

Ciprofloxacin 

Dosage Forms & Strengths

• 250, 500, 1000 mg (xl) 750mg tab, 200mg/100ml infusion, 400mg/200ml infusion

Trade names  : 

• Bactiflox, Floroxin,Cibrobay,Ciproflacin, Ciprolon, Ciproflox, Bactall ,Siprosan, Cipro, Ciprover, Quinox, Floxacin ,Ciproquin, Cipropharm, Omacip, Serviflox
• Cipromid, Ciprogen ,Ciprodar ,Floxar, Mecado ,Topistin, ufexil, cefloxine ,Ciprox

Therapeutic indication and dose :

Acute Sinusitis

• Mild/moderate: 500 mg PO q12hr or 400 mg IV q12hr for 10 days

Bone & Joint Infections

• Mild/moderate: 500 mg PO q12hr or 400 mg IV q12hr for ≥4-6 weeks
• Severe/complicated: 750 mg PO q12hr or 400 mg IV q8hr for ≥4-6 weeks

Chronic Bacterial Prostatitis

• Indicated for chronic bacterial prostatitis caused by Escherichia coli or Proteus mirabilis
• Mild/moderate: 500 mg PO q12hr or 400 mg IV q12hr for 28 days

Infectious Diarrhea

• Mild/moderate/severe: 500 mg PO q12hr for 5-7 days

Empirical Therapy in Febrile Neutropenic Patients

• Severe: 400 mg IV q8hr for 7-14 days

Intra-abdominal Infections

• Complicated: 500 mg PO q12hr or 400 mg IV q12hr for 7-14 days

Lower Respiratory Tract Infections

• Mild/moderate: 500 mg PO q12hr or 400 mg IV q12hr for 7-14 days
• Severe/complicated: 750 mg PO q12hr or 400 mg IV q8hr for 7-14 days

Nosocomial Pneumonia

• Mild/moderate/severe: 400 mg IV q8hr for 10-14 days

Skin/Skin Structure Infections

• Mild/moderate: 500 mg PO q12hr or 400 mg IV q12hr for 7-14 days
• Severe/complicated: 750 mg PO q12hr or 400 mg IV q8hr for 7-14 days

Urinary Tract Infections

• Acute uncomplicated: Immediate-release, 250 mg PO q12hr for 3 days; extended-release, 500 mg PO q24hr for 3 days
• Mild/moderate: 250 mg PO q12hr or 200 mg IV q12hr for 7-14 days
• Severe/complicated: 500 mg PO q12hr or 400 mg IV q12hr for 7-14 days

Urethral & Cervical Gonococcal Infections

• Uncomplicated: 250-500 mg PO once

Anthrax Infection

Postexposure therapy

• Inhalation (prophylaxis/postexposure): 500 mg PO q12hr or 400 mg IV q12hr for 60 days
• Cutaneous: 500 mg PO q12hr or 400 mg IV q12hr for 60 days

Plague

Indication for treatment and prophylaxis of plague due to Yersinia pestis

• 500-750 mg PO q12hr x14 days, OR
• 400 mg IV q8-12hr x 14 days

Contraindications:

• Hypersensitivity to the active substance

Pregnancy and lactation: 

• It is preferable to avoid the use of ciprofloxacin during pregnancy. 

Breast-feeding 

• Ciprofloxacin is excreted in breast milk. Due to the potential risk of articular damage, ciprofloxacin should not be used during breast-feeding

Side effects: 

• Nausea, Diarrhea, abdominal pain, insomnia

Paractamol

• Analgesic and antipyretics
• Not anti-inflammatory effect
• Suitable for Temperature between (37.5C – 38.5C)
• Safe under 6 months

Trade names  : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )

Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories,1g/100ml solution for infusion

Dose : 

Tablet, capsule : 

• 500mg tabs 1-2 tabs /cap every 6 hours

Syrup, suspension :

• < 5year  : 125mg/5ml susp (w/2) Every 4 – 6 hours
• 5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours 

Suppositories :

• <1Y : 125 mg supp Every 8 hours  (1 supp x 3 )
• >1Y : 250mg supp Every 8 hours ( 1supp x 3 )

Iv solution 1g/100ml :

• <10kg : 0 .75ml/kg 
• >10kg , <50kg :  1.5ml/kg
• >50kg : 100ml Slowly over 15 minute

Maximum dose : 4g daily 

Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding

Loratadine

Available forms:

• Loratan, clara, histal, Klarihist, Loreen, Lorine Lohist, Ramitin:10mg tab, 5mg/5ml syrup
• Tidilor, Claritine, Lorax :10mg tab, 1mg/1ml syrup
• Loratin, Restamine:10mg tab
• Lostamin: 5mg/5ml syrup

Indications:

• Relief of symptoms associated with allergic rhinitis, such as sneezing, nasal discharge (rhinorrhea) as well as ocular itching and burning.
• indicated for the relief of symptoms and signs of chronic urticaria and other allergic dermatologic disorders.

Dose:

• Adults and children 6 years and older who weigh more than 30kg : 1 x tablet once daily
• Adults and children over 12 years of age: 2 teaspoons (10 ml), once a day, with or without food.
• The dosage for children aged 2-12 is by weight:
• Body weight over 30 kg: 2 teaspoons (10 ml), once a day, with or without food.
• Body weight of 30 kg or less: one teaspoon (5 ml), once a day, with or without food.

Pregnancy and breast-feeding :

As a precautionary measure, it is preferable to avoid the use of Loratadine Tablets during pregnancy. Loratadine is excreted in breast milk so preferable to avoid the use in lactation

side effect:

• drowsiness  
• headache
• increased appetite 
• difficulty sleeping.

Otrivine

Otrivine Nasal Spray contains the active ingredient xylometazoline hydrochloride which helps to open up and clear the nasal passages by reducing the excessive nasal secretions and returning the swollen blood vessels to their normal size.

 Used in :

• nasal congestion (blocked nose, including colds)
• allergic rhinitis
• sinusitis.
• Not used>5 days Cause rebound congestion

Pregnancy : not  recommended

Available forms:

• Otrivin 0.1% spray/drop , .05% spray /drop
• Decozal 0.1% spray/drop , .05% spray /drop
• Xylomet 0.1% spray

Dose:

Adult

• 0.1% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child>6y

• 0.05% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child 6months-6y

• 0.05% Nasal drop 1drops in each nostrils up to 3 times daily