- Ampicillin 500mg capsules 1 x 4 x 10
- Advil cold and sinus 1- 2 caplets every 4 to 6 hours
- Aierxem 50mcg/dose nasal spray 2 sprays in each nostril once a day
If there are excessive secretions and sneezing add:
- Fenistil 4mg caps 1cap every 4-6 hours
If there is nasal obstruction add :
- Rinomest 6.5mg/ml spray 1puff 4-6 times daily
Ampicillin :
Dosage Forms & Strengths:
- 500mg capsule, 500mg vial, 250mg vial, 1g vial, 250mg /5ml suspension
Trade names :
- Ultracilin, Ampidar , Pamecil , Penbritin ,Standacillin
Therapeutic indication and dose :
Genitourinary Tract Infections (Excluding Gonorrhea)
- <40 kg: 50 mg/kg/day IV/IM divided q6-8hr
- ≥40 kg: 500 mg PO/IV/IM q6hr
Gastrointestinal Tract Infections
- <40 kg: 50 mg/kg/day IV/IM divided q6-8hr
- ≥40 kg: 500 mg IV/IM q6hr; larger doses may be necessary in severe or chronic infection
Urinary Tract Infection (ampicillin-susceptible Enterococcus; Off-label)
- 1-2 g IV q4-6hr with or without an aminoglycoside
Gonorrhea
- 3.5 g IV administered once simultaneously with 1 g of probenecid
Respiratory Tract Infections
≥40 kg
- 250-500 mg PO q6hr
- 250-500 mg IV/IM q6hr
<40 kg
- 25 to 50 mg/kg/day IV or IM divided q6-8hr
Bacterial Meningitis/Septicemia
- 150-200 mg/kg/day IV divided q6-8hr; initiate with IV infusion; may continue with IM injections if preferred; range 6-12 g/day
Group B Streptococcus (Off-label)
- Maternal dose for neonatal prophylaxis
- 2 g IV initially, followed by 1 g q4hr until delivery
Listeria Infection (Off-label)
- 2 g IV q4hr
Contraindications:
- History of hypersensitivity to beta-lactam antibiotics (e. g. Ampicillin, penicillin, cephalosporin).
Pregnancy and Breastfeeding :
- When antibiotic therapy is required during pregnancy and lactation, Ampicillin may be considered appropriate.
- Skin: Urticaria, pruritus of various etiology, endogenous eczema with previous medical diagnosis.
- Respiratory system: Seasonal (hay fever) and perennial rhinitis with previous medical diagnosis.
Common side effects:
- Hypersensitivity reactions: Skin rash, pruritus and urticarial, Purpura
- Nausea, vomiting and diarrhea
- Swelling of the tongue
Advil-Cold&Sinus Capsule
Ingredients: Ibuprofen – Pseudoephedrine
Product Description:
- Advanced formula for cold & sinus relief
Indications:
- Fast, temporary relief of the symptoms of colds including sore throat pain, sinus pain, nasal congestion, headache, fever, body aches and pains.
Dose:
Adults under 65 years and children over 12:
- 1 or 2 caplets every 4 to 6 hours as needed.
- not more six caplets in 24 hours
- not given to children under 12.
- not used longer than 3 days for a fever or 5 days for pain or cold symptoms.
Corticosteroids nasal spray (Fluticasone)
Available forms:
- Flixonase, Rhinase, Dalman, Avamys, Aierxem: 50mcg/dose
Indications:
corticosteroid indicated for the management of thenasal symptoms of perennial nonallergic rhinitis in adult and pediatric patients
aged 4 years and older.
Dose:
For intranasal use only. Recommended starting dosages:
- Adults: 2 sprays per nostril once daily (200 mcg per day).
- Adolescents and children aged 4 years and older: 1 spray per nostril oncedaily (100 mcg per day).
Dimetindene
Available forms:
- Fenistil: drop 1mg/1ml, 4mgcaps, 1mgtab
- Pedia fast: drop 0.1g/100ml, 0.01g/100ml syrup
- Alergin: drop 1mg/1ml (1 ml = 20 drops).
- Fencil: drop 1mg/1ml
- 1 ml contains dimetindene maleate 1 mg (1 ml = 20 drops).
Therapeutic indications
- Symptomatic treatment of allergic diseases:
- Relieve of itching associated with infectious diseases (e.g. chickenpox) with previous medical diagnosis or after an insect bite or stings.
Dose:
1mg/1ml oral drops, 0.1g/100ml drop:
- Adults :The recommended daily dose is 3 – 6 mg of dimetindene maleate divided into 3 doses,
- 20 –40 drops 3× a day.
- Paediatric The recommended daily dose for children 1 – 11 years is 0.1 mg dimetindene maleate/kg body
- 2 drops/kg/day divided into 3 doses.
1mg tablet:
- 1 to 2 milligrams three times daily
0.01g/100ml syrup:
- the recommended dose is 1 teaspoonful (5 ml) of a 0.01g/100ml syrup 3-4 times daily
4mg capsule :
- 1capsule once daily
Contraindications :
- Hypersensitivity to the active substance or to any of the excipientsInfants and children under 1 year of age.
pregnancy and lactation :
- Pregnancy There are no data about the use of dimetindene maleate during pregnancy.
- Dimetindene maleate should not be used in pregnant women unless the benefit of treating the mother outweighs the risk for the foetus
Breast-feeding :
- There is a well-founded presumption that dimetindene can be excreted in human milk. So its not recommended.
Side effect :
- Fatigue
- Somnolence, nervousness
Rinomist 6.5mg/ml nasal spray
- Sodium chloridenatural nasal decongestant spray
- is an over the counter (OTC) moisturizing nasal spray that relieves the symptoms of dry, irritated nasal mucosa due to nasal congestion, dry weather, smoking, colds, nose bleeds, and other similar conditions.
Dose:
- 1puffs 4-6 times daily
Pregnancy and lactation:
- Save
In Emergency room:
- Give antipyretic:
- Perflgan 1g/100ml intravenous injection :
Dose:
Pediatrics:
- <10kg : 0 .75ml/kg
- >10kg , <50kg : 1.5ml/kg
- >50kg : 100ml Slowly over 15 minute
Adult:
- 100ml Slowly over 15 minute
OR
- Diclofenac sodium injection 75 mg/3ml intramuscular injection :
Dose:
Pediatrics:
- > 1year : 1ml/20kg every 12 hour .
Adult:
- 25 to 75 mg(1-3ml) depending on the severity pain.
- If the pain still severe, you may decide to give a second injection after 6 hours.
- Give Antibiotic:
- Lincomycin 600mg/2ml
Dose:
Pediatrics:
- IV: 10-20 mg/kg/day divided q8-12hr
- IM: 10 mg/kg q12-24hr
Adult:
- IM: 600 mg q12-24hr
- IV: 600-1000 mg q8-12hr; not to exceed 8 g/day
OR
- Ceftriaxone injection
Dose:
Pediatrics:
- 50 mg/kg IM in single dose; not to exceed 1 g
Adult:
- 50 mg/kg IM once
- Persistent or treatment failures: 50 mg/kg IV/IM for 3 days
- Give Antihistamine In sneezing and rhinorrhea :
- Allerfin 10mg/ml IM injection :
Dose:
- 1-5 year : 25-5mg (½ ml )
- 6-12 year: 5-10mg (1ml )
- Adult : 10-20 mg (1-2 ml )
Acute sinusitis
Presentation :
- Purulent nasal discharge
- Nasal congestion or obstruction
- Facial congestion or fullness
- Facial pain or pressure
- Decreased sense of smell
- Fever
- Headache
- Ear pain
- fullness; halitosis; dental pain; cough; fatigue
Examination:
- Purulent nasal secretions
- Purulent posterior pharyngeal secretions
- Mucosal erythema
- Tenderness overlying sinuses
Lines of management :
- Antipyretics
- Antibiotics
- Symptomatic treatment:
- In nasal obstruction : use nasal decongestant
- In excessive secretions and sneezing : use antihistamine
- If not respond : Intranasal Corticosteroids :
- Helpful in reducing mucosal swelling of inflamed tissue and facilitating sinus drainage because of an anti-inflammatory effect