- Azithromycin 500mg capsule 1x1x3
- Panadol cold and flu 1-2 tablet 2 times daily
- Nasonex . 05% nasal spray 2 sprays in each nostril once a day
Azithromycin
Dosage Forms & Strengths:
- 250mg ,500mg capsule and tablet, 500mg vial, 200mg/5ml suspension, 300mg /7.5ml suspension
Trade names :
Zocin, Zimax , Zomax, Azomycin, Azi_once, Zithromax, Azitam, Zithrova, Zaha, Zilacid, Azicure, Azomyne , Azox
Therapeutic indication and dose :
Community-acquired Pneumonia
- 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5
Pharyngitis or Tonsillitis
- 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5
Uncomplicated skin/skin structure
- 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5
Acute bacterial exacerbations of chronic obstructive pulmonary disease
- 500 mg PO qDay for 3 days OR
- 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5
Acute bacterial sinusitis
- 500 mg PO qDay x 3 days
Genital Ulcer Disease (Chancroid)
- 1000 mg PO x 1 dose
Nongonococcal or Gonococcal Urethritis and Cervicitis
- 1000 mg PO x 1 dose
Cat Scratch Disease (Off-label)
- >45.5 kg: 500 mg PO once, then 250 mg once daily for 4 days
Pertussis (Off-label)
- 500 mg PO once, then 250 mg once daily for 4 days
Endocarditis (Off-label)
Prophylaxis
- 500 mg PO 30-60 min before procedure
Contraindications:
- Hypersensitivity to azithromycin, erythromycin, any macrolide
Pregnancy:
- The safety of azithromycin has not been confirmed with regard to the use of the active substance during pregnancy. Therefore, Azithromycin should only be used during pregnancy if the benefit outweighs the risk
Breastfeeding :
- Azithromycin has been reported to be secreted into human breast milk
- Because it is not known whether azithromycin may have adverse effects on the breast-fed infant, nursing should be discontinued during treatment with Azithromycin. Among other things diarrhea, fungus infection of the mucous membrane is possible in the nursed infant. It is recommended to discard the milk during treatment and up until 2 days after discontinuation of treatment. Nursing may be resumed thereafter.
Common side effects:
- Anorexia
- Dizziness, headache, paranesthesia, dysgeusia
- Visual impairment, Deafness
- Vomiting, dyspepsia
- Rash, pruritus
Panadol cold and flu
Ingredients:
- Active Ingredients: Paracetamol 500 mg, Pseudoephedrine Hydrochloride 30 mg, Chlorphenamine Maleate 2 mg.
- Other non-active ingredients: Silicon dioxide, Stearic acid, Sodium benzoate, Povidone, Pregelatinised starch, Maize starch, Talc.
used for:
- This product consists of three active ingredients: paracetamol, chlorpheniramine and pseudoephedrine hydrochloride.
- Paracetamol is a medication that belongs to a class of medications known as analgesics (pain relievers) and antipyretics (fever reducers).
- Chlorpheniramine is an antihistamine that acts by decreasing the effects of histamine in your body and therefore helps in relieving allergy signs and symptoms, like, sneezing, watery eyes, itching, and runny nose.
- Pseudoephedrine is a medication that belongs to a class of medicines known as “decongestants” and acts by decreasing nasal stuffiness that you may experience during cold and flu.
- It is used for the night time relief from cold and flu symptoms.
It is used for the relief of the following indications:
- Headache
- Congestion and sinus pain
- Sneezing
- Body aches
- Itchy and watery eyes
- Blocked and runny nose
- Fever
Contraindication:
- In allergy to Paracetamol, or Chlorpheniramine, or Pseudoephedrine Hydrochloride, other antihistamines or any of the ingredients in this medicine.
- In taking other paracetamol containing products or other antihistamines or cough or cold and flu medications or decongestants. Make sure not to exceed the dose.
- In high blood pressure or severe kidney or heart problems.
Possible side effects:
- allergic reaction, like rash and itching, signs of breathing problems like difficulty breathing.
- Other side effects include drowsiness or sleepiness, difficulty sleeping, fatigue, headache, hallucinations, twitching or jerking muscles, nervousness, blurred vision, difficulty concentrating, excitability, dizziness, nausea, indigestion or vomiting, restlessness, dry mouth nose and throat, rapid heart rate, loss of coordination, nervousness and irritability.
Dose:
Adults and children aged 12 years and over:
- 1 to 2 tablets every 4 to 6 hours as needed. not to exceed 8 tablets within 24 hours.
- not more than 4 doses in 24 hours. Doses should be spaced by at least 4 hours.
Children under 12 years:
- not given to children below 12 years of age.
Corticosteroids nasal spray (Mometasone)
- help to relieve inflammation(swelling and irritation of the nose), sneezing, itching and a blocked up or runny nose.
Available forms:
- Nasonex, Tabunex, Sinocort: 05% nasal spray
Indications:
- to treat the symptoms of seasonal allergic rhinitis (also called hayfever) and perennial (long lasting) rhinitis in adults and children aged 3 and older;
- to treat nasal polyps in adults aged 18 and over
Dose:
Adult:
- recommended dose is two sprays in each nostril once a day.
- Once symptoms are controlled, dose reduction to one spray in each nostril may be effective for maintenance.
- may increase to the dose; the maximum daily dose is four sprays into each nostril once a day.
Children aged 3 to 11 years :
- the usual dose is one spray into each nostril once daily.
- May used some days before the start of the allergy season, as this will help to prevent allergic rhinitis symptoms from occurring.
- Prophylaxis must be initiated up to 2-4 weeks prior to the anticipated start of the allergy season.
- Benefit of treatment may be achieved in the first two days.
- Maximum benefit is achieved within 1-2 weeks following initiation of treatment. Therefore, patients should continue regular use to achieve full therapeutic benefit.
For patients who use MOMEX® at regular intervals for treatment of allergic rhinitis,:
- recommended dose is a spray into each nostril once a day. For children between the ages of 2 and 11 years the usual recommended dose is one spray in each nostril once a day.
In Emergency room:
- Give antipyretic:
- Perflgan 1g/100ml intravenous injection :
Dose:
Pediatrics:
- <10kg : 0 .75ml/kg
- >10kg , <50kg : 1.5ml/kg
- >50kg : 100ml Slowly over 15 minute
Adult:
- 100ml Slowly over 15 minute
OR
- Diclofenac sodium injection 75 mg/3ml intramuscular injection :
Dose:
Pediatrics:
- > 1year : 1ml/20kg every 12 hour .
Adult:
- 25 to 75 mg(1-3ml) depending on the severity pain.
- If the pain still severe, you may decide to give a second injection after 6 hours.
- Give Antibiotic:
- Lincomycin 600mg/2ml
Dose:
Pediatrics:
- IV: 10-20 mg/kg/day divided q8-12hr
- IM: 10 mg/kg q12-24hr
Adult:
- IM: 600 mg q12-24hr
- IV: 600-1000 mg q8-12hr; not to exceed 8 g/day
OR
- Ceftriaxone injection
Dose:
Pediatrics:
- 50 mg/kg IM in single dose; not to exceed 1 g
Adult:
- 50 mg/kg IM once
- Persistent or treatment failures: 50 mg/kg IV/IM for 3 days
- Give Antihistamine In sneezing and rhinorrhea :
- Allerfin 10mg/ml IM injection :
Dose:
- 1-5 year : 25-5mg (½ ml )
- 6-12 year: 5-10mg (1ml )
- Adult : 10-20 mg (1-2 ml )
Acute sinusitis
Presentation :
- Purulent nasal discharge
- Nasal congestion or obstruction
- Facial congestion or fullness
- Facial pain or pressure
- Decreased sense of smell
- Fever
- Headache
- Ear pain
- fullness; halitosis; dental pain; cough; fatigue
Examination:
- Purulent nasal secretions
- Purulent posterior pharyngeal secretions
- Mucosal erythema
- Tenderness overlying sinuses
Lines of management :
- Antipyretics
- Antibiotics
- Symptomatic treatment:
- In nasal obstruction : use nasal decongestant
- In excessive secretions and sneezing : use antihistamine
- If not respond : Intranasal Corticosteroids :
- Helpful in reducing mucosal swelling of inflamed tissue and facilitating sinus drainage because of an anti-inflammatory effect