1. Cephalexin 250 mg capsule 1×4 or 500 mg capsule  1×2

1. Doloraz 400mg tablet 1 x 3 until fever subside

3. Tabunex .05% nasal spray 2 sprays in each nostril once a day

If there are excessive secretions and sneezing   add:

• Xyzal 5mg orally once a day in the evening

 If there is nasal obstruction add :

• Decozal 0.1% spray/drop 2-3 drops in each nostrils up to 3 times daily up to 7 days

Cephalexin

Dosage Forms & Strengths:

• 250mg capsule, 500mg capsule , 1g tablet, 125mg/5ml suspension, 250mg/5ml suspension

Trade names  :

• Lexin, Cephadar, Unilexin, Keflex, Pharmexin, Flexin

Therapeutic indication and dose :

Genitourinary Tract Infections

• 250 mg PO q6hr; dosage range, 1-4 g/day in divided doses

Bone Infections

• 250 mg PO q6hr; dosage range, 1-4 g/day in divided doses

Uncomplicated Cystitis

• 250 mg PO q6hr or 500 mg PO q12hr; dosage range, 1-4 g/day in divided doses

Otitis Media

• 250 mg PO q6hr; dosage range, 1-4 g/day in divided doses

Skin/Skin Structure Infections

• 250 mg PO q6hr or 500 mg PO q12hr; dosage range, 1-4 g/day in divided doses

Respiratory Tract Infections

• 250 mg PO q6hr; dosage range, 1-4 g/day in divided doses

Streptococcal Pharyngitis

• 250 mg PO q6hr or 500 mg PO q12hr; dosage range, 1-4 g/day in divided doses

Cellulitis and Mastitis

• 500 mg PO q6hr; dosage range, 1-4 g/day in divided doses 500 mg PO q6hr for 7 days

Contraindications:

• Allergy to the cephalosporins group of antibiotics
• Cephalosporins should be given with caution to penicillin-sensitive patients, as there is some evidence of partial cross-allergenicity between the penicillins and the cephalosporins. 
• Cefalexin is contraindicated in patients with acute porphyria. 

Pregnancy: Caution should be exercised when prescribing for the pregnant patient.

Breastfeeding: 

• The excretion of cefalexin in human breast milk increased up to 4 hours following a 500mg dose. Caution should be exercised when cefalexin is administered to a nursing mother, possible effects to the infant include modification of bowel flora. 

Side effects:

• Pseudomembranous colitis
• Nausea and vomiting. 
• Diarrhea
• Dyspepsia and abdominal pain

Brufen

• Analgesic and antipyretics
• Has anti-inflammatory effect
• Suitable for Temperature( 38-38.5) C
• Not save under 6 months
• Taken After meal
  • 200mg every 6-8 hours, May increase to 400mg every 6-8hours 

Trade names :  brufen (Taskine , Doloraz, Iburam,Remofen ,Ibugesic,Sapofen,Perofen,Rupan,Bulkaprofen,Advil liquid-gel , Profast, Nashat ,Midofen,Ibusoft).

Other concentration: 800mg and 400mg tablet 600mg tablet, 100mg/5ml syrup

Dose:

Tablets :

Syrup, suspension :

• 100mg/5ml Syrup(Wx0.375) every 6-8hours

Oral drops :

40mg/1ml 

• 6-11 months  : 1.25ml every 8 hours
• 12-23months : 1.8ml every 8 hours

Maximum dose : 3200 mg per day  

Contraindication: 

• History of hypersensitivity to aspirin or other NSAIDs
• current or recent stomach ulcer
• severe heart failure.
• severe liver disease

Pregnancy : not usually recommended in pregnancy

Corticosteroids nasal spray (Mometasone)

• help to relieve inflammation(swelling and irritation of the nose), sneezing, itching and a blocked up or runny nose.

Available forms:

• Nasonex, Tabunex, Sinocort: 05% nasal spray

 Indications:

• to treat the symptoms of seasonal allergic rhinitis (also called hayfever) and perennial (long lasting) rhinitis in adults and children aged 3 and older;
•  to treat nasal polyps in adults aged 18 and over

Dose:

Adult:

• recommended dose is two sprays in each nostril once a day. 
• Once symptoms are controlled, dose reduction to one spray in each nostril may be effective for maintenance.
• may  increase to  the dose; the maximum daily dose is four sprays into each nostril once a day. 

Children aged 3 to 11 years :

• the usual dose is one spray into each nostril once daily. 
• May used some days before the start of the allergy season, as this will help to prevent  allergic rhinitis symptoms from occurring. 
• Prophylaxis must be initiated up to 2-4 weeks prior to the anticipated start of the allergy season.
•  Benefit of treatment may be achieved in the first two days.
•  Maximum benefit is achieved within 1-2 weeks following initiation of treatment. Therefore, patients should continue regular use to achieve full therapeutic benefit. 

For patients who use MOMEX® at regular intervals for treatment of allergic rhinitis,:

• recommended dose is a spray into each nostril once a day. For children between the ages of 2 and 11 years the usual recommended dose is one spray in each nostril once a day.

Levocetirizine

Available forms:

• Xyzal, Levosyn, levar, Levozal, Zolix, Cetazal      :5mg tab
• Layal  : 5mg tab, 2.5 mg /5ml syrup
• L-cet : 5mg tab, 0.5mg/ml syrup
• Hpi –levocetirizine : 5mg tab
• Lesonal :  5mg tab, 0.5 mg /ml syrup

Theraputic indications:

• allergic rhinitis (including persistent allergic rhinitis);
• nettle rash (urticaria).

Dose:

Adults :

• 5 milligrams (mg) or 10 mL) (2 teaspoons) once a day taken in the evening. Some patients may be given 2.5 mg or 5 mL (1 teaspoon) once a day taken in the evening.

Children 6 to 11 years of age : 

• 2.5 mg or 5 mL (1 teaspoon) once a day taken in the evening. Do not take more than 2.5 mg per day.

Children 6 months to 5 years of age :

•  1.25 mg or 2.5 mL (1/2 teaspoon) once a day taken in the evening. Do not take more than 1.25 mg per day.

For oral dosage form (tablets):

• Adults and children 12 years of age and older—5 mg (1 tablet) once a day taken in the evening. Some patients may be given 2.5 mg (1/2 tablet) once a day taken in the evening. Do not take more than 5 mg per day.
• Children 6 to 11 years of age—2.5 mg (1/2 tablet) once a day taken in the evening. Do not take more than 2.5 mg per day.

Side effect:

• dry mouth,
• headache,
• tiredness
• somnolence/drowsiness.

Otrivine

Otrivine Nasal Spray contains the active ingredient xylometazoline hydrochloride which helps to open up and clear the nasal passages by reducing the excessive nasal secretions and returning the swollen blood vessels to their normal size.

 Used in :

• nasal congestion (blocked nose, including colds)
• allergic rhinitis
• sinusitis.
• Not used>5 days Cause rebound congestion

Pregnancy : not  recommended

Available forms:

• Otrivin 0.1% spray/drop , .05% spray /drop
• Decozal 0.1% spray/drop , .05% spray /drop
• Xylomet 0.1% spray

Dose:

Adult

• 0.1% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child>6y

• 0.05% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child 6months-6y

• 0.05% Nasal drop 1drops in each nostrils up to 3 times daily