1. Amoxicillin 500 mg capsule 1x2x10-14 or 250 mg capsule 1x3x10-14

2. Revenin 500mg tablet 1x 4 up to 2 x 4 until fever subside

     If there are excessive secretions and sneezing   add:

• Levocetirizine 5mg tab 1×1 in the evening

     If there is nasal obstruction add :

• Otrivin 0.1% spray/drop 2-3 drops in each nostrils up to 3 times daily not more than 7 days

Amoxicillin :

Dosage Forms & Strengths

1000mg, 1g, 500mg, 750mg 625mg tablets, 500mg, 250mg capsules, 375mg/5ml suspension ,250mg/5ml suspension, 125mg/5ml suspension 

Trade names  : Amoxil, Moxiram, Penamox, Ultramox, Moxilen, Hymox, Amoxapen, Julphamox, Ospamox, Amoxydar, Amoxibel

Therapeutic indication and dose :

Ear, Nose, & Throat Infections

Mild to moderate infections

• 500 mg PO q12hr or 250 mg PO q8hr for 10-14 days

Severe infections

• 500 mg PO q8hr for 10-14 days

Genitourinary Tract Infections

Mild to moderate infections

• 500 mg PO q12hr or 250 mg PO q8hr

Severe infections

• 500 mg PO q8hr

Skin & Skin Structure Infections

Mild to moderate infections

• 500 mg PO q12hr or 250 mg PO q8hr

Severe infections

• 500 mg PO q8hr

Lower Respiratory Tract Infections

• 500 mg PO q8hr for 10-14 days

Helicobacter Pylori

H pylori infection and active or 1-year history of duodenal ulcer

Triple therapy

• 1 g PO q12hr for 14 days with lansoprazole (30 mg) and clarithromycin (500 mg)

Dual therapy

• 1 g PO q8hr for 14 days with lansoprazole (30 mg) in patients intolerant of, or resistant to, clarithromycin

Infective Endocarditis

Prophylaxis

• 2 g PO 30-60 min before procedure

Chlamydial Infection in Pregnant Women 

• First trimester: 500 mg PO q8hr for 7 days

Contraindications:

• Hypersensitivity to penicillin’s, semi-synthetic penicillin’s or cephalosporin. 
• Liver problems
• Renal impairment

Pregnancy:

• Category B

Breastfeeding :

• Amoxicillin is excreted into breast milk in small quantities
• Diarrhea and fungus infection of the mucous membranes are possible in the breast-fed infant, so that breast-feeding might have to be discontinued. 

Common side effects:

• Anaphylaxis
• Anemia
• AST/ALT elevation
• Mucocutaneous candidiasis
• Diarrhea
• Headache
• Nausea
• Vomiting
• Rash
• Pseudomembranous colitis

Paractamol

• Analgesic and antipyretics
• Not anti-inflammatory effect
• Suitable for Temperature between (37.5C – 38.5C)
• Safe under 6 months

Trade names  : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )

Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories, 1g/100ml solution for infusion

Dose : 

Tablet, capsule : 

• 500mg tabs 1-2 tabs /cap every 6 hours

Syrup, suspension :

• < 5year  : 125mg/5ml susp (w/2) Every 4 – 6 hours
• 5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours 

Suppositories :

• <1Y : 125 mg supp Every 8 hours  (1 supp x 3 )
• >1Y : 250mg supp Every 8 hours ( 1supp x 3 )

Iv solution 1g/100ml :

• <10kg : 0 .75ml/kg 
• >10kg , <50kg :  1.5ml/kg
• >50kg :  100ml Slowly over 15 minute

Maximum dose : 4g daily 

Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding 

Levocetirizine

Available forms:

• Xyzal, Levosyn, levar, Levozal, Zolix, Cetazal      :5mg tab
• Layal  : 5mg tab, 2.5 mg /5ml syrup
• L-cet : 5mg tab, 0.5mg/ml syrup
• Hpi –levocetirizine : 5mg tab
• Lesonal :  5mg tab, 0.5 mg /ml syrup

Theraputic indications:

• allergic rhinitis (including persistent allergic rhinitis);
• nettle rash (urticaria).

Dose:

Adults :

• 5 milligrams (mg) or 10 mL) (2 teaspoons) once a day taken in the evening. Some patients may be given 2.5 mg or 5 mL (1 teaspoon) once a day taken in the evening.

Children 6 to 11 years of age : 

• 2.5 mg or 5 mL (1 teaspoon) once a day taken in the evening. Do not take more than 2.5 mg per day.

Children 6 months to 5 years of age :

•  1.25 mg or 2.5 mL (1/2 teaspoon) once a day taken in the evening. Do not take more than 1.25 mg per day.

For oral dosage form (tablets):

• Adults and children 12 years of age and older—5 mg (1 tablet) once a day taken in the evening. Some patients may be given 2.5 mg (1/2 tablet) once a day taken in the evening. Do not take more than 5 mg per day.
• Children 6 to 11 years of age—2.5 mg (1/2 tablet) once a day taken in the evening. Do not take more than 2.5 mg per day.

Side effect:

• dry mouth,
• headache,
• tiredness
• somnolence/drowsiness.

      Otrivine

Otrivine Nasal Spray contains the active ingredient xylometazoline hydrochloride which helps to open up and clear the nasal passages by reducing the excessive nasal secretions and returning the swollen blood vessels to their normal size.

 Used in :

• nasal congestion (blocked nose, including colds)
• allergic rhinitis
• sinusitis.
• Not used>5 days Cause rebound congestion

Pregnancy : not  recommended

Available forms:

• Otrivin  0.1% spray/drop , .05% spray /drop
• Decozal 0.1% spray/drop , .05% spray /drop
• Xylomet 0.1% spray

Dose:

Adult

• 0.1% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child>6y

• 0.05% Nasal drop 2-3 drops in each nostrils up to 3 times daily

Child 6months-6y

• 0.05% Nasal drop 1drops in each nostrils up to 3 times daily