Rx
Notes
In emergency
Disease annotations
Rx
- Avoid exposure to allergen
- If there are excessive secretions and sneezing add:
- Hydroxyzine 25mg 1 tab every 8-6 hours
- If there is nasal obstruction add :
- Sterimar Isotonic sea water spray 1puff 4-6 times
- In more sever cases add:
- Unicast 10mg once daily at bed time
- Nasonex .05% nasal spray 2 sprays in each nostril once a day
Notes
Corticosteroids nasal spray (Mometasone)
- help to relieve inflammation(swelling and irritation of the nose), sneezing, itching and a blocked up or runny nose.
Available forms:
- Nasonex, Tabunex, Sinocort: 05% nasal spray
Indications:
- to treat the symptoms of seasonal allergic rhinitis (also called hayfever) and perennial (long lasting) rhinitis in adults and children aged 3 and older;
- to treat nasal polyps in adults aged 18 and over
Dose:
Adult:
- recommended dose is two sprays in each nostril once a day.
- Once symptoms are controlled, dose reduction to one spray in each nostril may be effective for maintenance.
- may increase to the dose; the maximum daily dose is four sprays into each nostril once a day.
Children aged 3 to 11 years :
- the usual dose is one spray into each nostril once daily.
- May used some days before the start of the allergy season, as this will help to prevent allergic rhinitis symptoms from occurring.
- Prophylaxis must be initiated up to 2-4 weeks prior to the anticipated start of the allergy season.
- Benefit of treatment may be achieved in the first two days.
- Maximum benefit is achieved within 1-2 weeks following initiation of treatment. Therefore, patients should continue regular use to achieve full therapeutic benefit.
For patients who use MOMEX® at regular intervals for treatment of allergic rhinitis,:
- recommended dose is a spray into each nostril once a day. For children between the ages of 2 and 11 years the usual recommended dose is one spray in each nostril once a day.
Hydroxyzine
Available forms:
- Atarax :25mg tab, 10mg/5ml syrup
- Newrax :10mg/5ml syrup
Therapeutic indications:
- Anxiety in adults
- Itching (pruritus) caused by allergic reactions in adults and children.
Dose :
- In adults the maximum daily dose is 100 mg (4 tablets) per day
Adults
For anxiety:
- The usual dose is ½ tablet at breakfast, ½ tablet at lunch and 1 tablet in the evening
- doctor may increase this to a maximum of 4 tablets taken three times a day.
For pruritis (itchiness of the skin):
- The usual dose is 1 tablet before going to bed
- doctor may increase this to 1 tablet three or four times a day
Children
- In children up to 40 kg, the maximum daily dose is 2 mg/kg/day.
For pruritis :
- The usual dose is 0.5 mg per kg of body weight twice a day
- doctor may increase this to a maximum of 1 mg per kg of body weight twice a day
The elderly
- In the elderly, the maximum daily dose is 50 mg (2 tablets) per day.
- The usual starting dose is 25 mg (1 tablet) a day
Contraindication :
- allergy to hydroxyzine hydrochloride or any of the other ingredients
- allergy to cetirizine, other piperazine derivatives, aminophylline or ethylenediamine
- pregnancy or breastfeeding
- porphyria.(A blood disease that can cause stomach pain, vomitingand mental disturbances such as depression
- ECG (electrocardiogram) shows a heart rhythm problem called “QT interval prolongation”
Pregnancy and breastfeeding :
- Not recommended in pregnancy or breastfeeding
Side effect:
- feeling sleepy
- dry mouth, feeling tired, headache
Sterimar Isotonic sea water spray
- Is a natural nasal decongestant spray
- Is an isotonic filtered sea water solution, 100% natural and free from preservatives
- Restores natural moisture of the nose (air conditioning, heating, travel). To assist when ENT disorders (sinusitis, colds, hayfever, allergies, dry & stuffy noses).
Dose:
- 1puffs 2 to 6 times a day in each nostril as required or as needed.
Pregnancy and lactation:
- Save
Montelukast
Available forms :
- Singulair
- Lukast
- Unicast
- Sincast
- Motrinex
- 4mg 5mg, 10mg Chewable tab
Action:
- Montelukast is in the leukotriene receptor antagonist family of medications. It works by blocking the action of leukotriene D4 in the lungs resulting in decreased inflammation and relaxation of smooth muscle
- Leukotrienes cause tightening of airway muscles and the production of excess mucus and fluid. These chemicals play a key role in allergies, allergic rhinitis, and asthma, also causing a tightening of your airways, making it difficult to breathe.
Indications
- Indicated in the treatment of asthma as add-on therapy in adults and adolescents from 15 years of age and older with mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids and in whom “as-needed” short acting β-agonists provide inadequate clinical control of asthma.
- Montelukast Film-coated tablet can also provide symptomatic relief of seasonal allergic rhinitis.
- Indicated in the prophylaxis of asthma in which the predominant component is exercise-induced bronchoconstriction.
Pregnancy
- Montelukast may be used during pregnancy only if it is considered to be clearly essential.
Lactation
- Studies in rats have shown that montelukast is excreted in milk. It is not known if montelukast is excreted in human milk.
- May be used in breast-feeding only if it is considered to be clearly essential.
- Side effects:
- Headache
- Abdominal pain
- Upper respiratory infection
- Diarrhea, nausea, vomiting
- Elevated levels of serum transaminases (ALT, AST)
- Rash
- Pyrexia
Dose:
- Adult: 10mg once daily at bed time
- Children 6-14y: 5mg once daily at bed time
- 2-5 y: 4mg once daily at bed time
In emergency
In Emergency room:
- Give Antihistamine In sneezing and rhinorrhea :
- Allerfin 10mg/ml IM injection :
Dose:
- 1-5 year : 25-5mg (½ ml )
- 6-12 year: 5-10mg (1ml )
- Adult : 10-20 mg (1-2 ml )
- Give Dexamethasone 4mg/1ml
Dose:
Pediatrics:
- 0.3 mg/kg/day IV / IM divided q6hr or q12hr
Adult:
- 4-8 mg IM /IV
Disease annotations
Allergic rhinitis
Presentation :
- Rhinorrhea
- Repetitive sneezing
- nasal congestion, obstruction
- postnasal drainage
- Pruritus
- Itching of the palate, nose, ears, eye
- Snoring
- Frequent sore throats
- Cough
- Headache
- Itching redness watery eyes
Lines of management :
- Avoid exposure to allergens
- In excessive secretions and sneezing: oral antihistamine
- If nasal obstruction: Nasal decongestant
- For ocular symptoms: intranasal antihistamine
- If Symptoms persist and affect quality of life: Intranasal Corticosteroid
- Sever and persistent symptoms: Intranasal Corticosteroid + oral or intranasal antihistamine+ Oral leukotriene receptors antagonist