Rx
Notes
In emergency
Disease annotations
Rx
- Avoid exposure to allergen
- If there are excessive secretions and sneezing add:
- Promet 25mg tab 1tab at night
- If there is nasal obstruction add :
- Free breath 7.1mg/1ml spray1puffs 4-6 times daily
Notes
Promethazine
Available forms:
- Histazin : 5mg/5ml syrup, 25mg tab
- Promet: 25mg tab
- Promethazine: 50mg/2ml for iv,im injection
Therapeutic indications
- As symptomatic treatment for allergic conditions of the upper respiratory tract and skin including allergic rhinitis, urticaria and anaphylactic reactions to drugs and foreign proteins.
- As an antiemetic.
- For short term use in treatment of insomnia in adults.
- For short term use as a paediatric sedative.
The usual doses are:
25mg tablet:
- Adults and Children>10 years : Start with 1 tablet (25 mg) taken at night. This maybe increased to a maximum of 1 tablet (25 mg) twice a dayif necessary.
- Children 5-10 years: A single tablet (25 mg) given at night. DO NOT give more than 25 mg per day.
50mg/2ml for iv,im injection
- Adult : 25 mg; may be repeated in 2 hours when necessary; switch to PO as soon as possible
- Pediatrics≥2 years: 12.5-25 mg IM at bedtime
5mg/5ml syrup:
- 2-5 years: 5-15 mg(1-3ml) daily in 1 or 2 divided doses
- >5-10 years : 10-25(2-5ml) mg daily in 1 or 2 divided doses
Contraindications
- should not be used in patients in coma or suffering from CNS depression of any cause.
- should not be given to patients with a known hypersensitivity to any of the excipients.
- contraindicated for use in children less than two years of age because of the potential for fatal respiratory depression..
pregnancy and lactation
- should not be used in pregnancy unless the physician considers it essential.
- The use is not recommended in the 2 weeks prior to delivery in view of the risk of irritability and excitement in the neonate.
- Available evidence suggests that the amount excreted in milk is insignificant. However, there are risks of neonatal irritability and excitement.
Side effects
- drowsiness, dizziness, restlessness, headaches, nightmares, tiredness, and disorientation. blurred vision, dry mouth and urinary retention
Free breath 7.1mg/1ml nasal spray
- Metered dose nasal spray
- sea water natural nasal decongestant spray
- Physiological solution for rinsing the nose
- Makes the breathing easier
- Free Breath Metered Dose Nasal Spray moisturizes the nose and improves comfort during flight. Using this product daily can help restore and optimize this self-cleaning system.
- Helps to stimulate the body’s natural shield
- Natural way to relieve congestion
- Does not contain any medication, just salt and water
Dose:
- 1puffs 4-6 times daily
In emergency
In Emergency room:
- Give Antihistamine In sneezing and rhinorrhea :
- Allerfin 10mg/ml IM injection :
Dose:
- 1-5 year : 25-5mg (½ ml )
- 6-12 year: 5-10mg (1ml )
- Adult : 10-20 mg (1-2 ml )
- Give Dexamethasone 4mg/1ml
Dose:
Pediatrics:
- 0.3 mg/kg/day IV / IM divided q6hr or q12hr
Adult:
- 4-8 mg IM /IV
Disease annotations
Allergic rhinitis
Presentation :
- Rhinorrhea
- Repetitive sneezing
- nasal congestion, obstruction
- postnasal drainage
- Pruritus
- Itching of the palate, nose, ears, eye
- Snoring
- Frequent sore throats
- Cough
- Headache
- Itching redness watery eyes
Lines of management :
- Avoid exposure to allergens
- In excessive secretions and sneezing: oral antihistamine
- If nasal obstruction: Nasal decongestant
- For ocular symptoms: intranasal antihistamine
- If Symptoms persist and affect quality of life: Intranasal Corticosteroid
- Sever and persistent symptoms: Intranasal Corticosteroid + oral or intranasal antihistamine+ Oral leukotriene receptors antagonist