Rx
Notes
In emergency
Disease annotations
Rx
- Avoid exposure to allergen
- In excessive nasal secretions (Rinorrhea,sneezing,itching):
- Fenistil drop 1mg/1ml ( 2 drops/kg/day divided into 3 doses)
- In nasal obstruction:
- Apisal 9mg/ml drop 1drop 4-6 times daily
Notes
Dimetindene
Available forms:
- Fenistil: drop 1mg/1ml, 4mgcaps, 1mgtab
- Pedia fast: drop 0.1g/100ml, 0.01g/100ml syrup
- Alergin: drop 1mg/1ml (1 ml = 20 drops).
- Fencil: drop 1mg/1ml
- 1 ml contains dimetindene maleate 1 mg (1 ml = 20 drops).
Therapeutic indications
- Symptomatic treatment of allergic diseases:
- Skin: Urticaria, pruritus of various etiology, endogenous eczema with previous medical diagnosis.
- Respiratory system: Seasonal (hay fever) and perennial rhinitis with previous medical diagnosis.
- Relieve of itching associated with infectious diseases (e.g. chickenpox) with previous medical diagnosis or after an insect bite or stings.
Dose:
1mg/1ml oral drops, 0.1g/100ml drop:
- Adults :The recommended daily dose is 3 – 6 mg of dimetindene maleate divided into 3 doses,
- 20 –40 drops 3× a day.
- Paediatric The recommended daily dose for children 1 – 11 years is 0.1 mg dimetindene maleate/kg body
- 2 drops/kg/day divided into 3 doses.
1mg tablet:
- 1 to 2 milligrams three times daily
0.01g/100ml syrup:
- the recommended dose is 1 teaspoonful (5 ml) of a 0.01g/100ml syrup 3-4 times daily
4mg capsule :
- 1capsule once daily
Contraindications :
- Hypersensitivity to the active substance or to any of the excipientsInfants and children under 1 year of age.
pregnancy and lactation :
- Pregnancy There are no data about the use of dimetindene maleate during pregnancy.
- Dimetindene maleate should not be used in pregnant women unless the benefit of treating the mother outweighs the risk for the foetus
Breast-feeding :
- There is a well-founded presumption that dimetindene can be excreted in human milk. So its not recommended.
Side effect :
- Fatigue
- Somnolence, nervousness
Apisal 9mg/ml drop, 7.4mg/ml spray
- Nasal decongestant
- is a safe drug-free physiological saline solution
- can be used as often as needed, to cleanse and moisturize nasal passages and help in removing incrustations, bacteria, viruses, allergens or irritants entrapped in the nasal mucosa.
- Nasal Dryness & Congestion
- relieves nasal congestion by thinning mucus and moisturizes membranes
Dose in adult and pediatrics:
- 1puffs /drop 4-6 times daily
Pregnancy and lactation:
- Save
In emergency
In Emergency room:
- Give Antihistamine In sneezing and rhinorrhea :
- Allerfin 10mg/ml IM injection :
Dose:
- 1-5 year : 25-5mg (½ ml )
- 6-12 year: 5-10mg (1ml )
- Adult : 10-20 mg (1-2 ml )
- Give Dexamethasone 4mg/1ml
Dose:
Pediatrics:
- 0.3 mg/kg/day IV / IM divided q6hr or q12hr
Adult:
- 4-8 mg IM /IV
Disease annotations
Allergic rhinitis
Presentation :
- Rhinorrhea
- Repetitive sneezing
- nasal congestion, obstruction
- postnasal drainage
- Pruritus
- Itching of the palate, nose, ears, eye
- Snoring
- Frequent sore throats
- Cough
- Headache
- Itching redness watery eyes
Lines of management :
- Avoid exposure to allergens
- In excessive secretions and sneezing: oral antihistamine
- If nasal obstruction: Nasal decongestant
- For ocular symptoms: intranasal antihistamine
- If Symptoms persist and affect quality of life: Intranasal Corticosteroid
- Sever and persistent symptoms: Intranasal Corticosteroid + oral or intranasal antihistamine+ Oral leukotriene receptors antagonist