1. Clarithromycin 250 mg/5ml suspension( Wx 0.15)x2x10
2. Brufen 100mg/5ml  syrup (Wx0.375) + Paracetamol ( Revanin) 250mg/5ml Syrup (w/4)  alternately every 6 hours  until fever subside

Clarithromycin

Otitis Media

• <6 months: Safety and efficacy not established
• ≥6 months: 15 mg/kg/day PO divided q12hr for 10 days; not to exceed 500 mg/dose

Community-Acquired Pneumonia

• <3 months: Safety and efficacy not established 
• ≥3 months: 15 mg/kg/day PO divided q12hr for 10 days; not to exceed 500 mg/dose 

Sinusitis

• <6 months: Safety and efficacy not established
• ≥6 months: 15 mg/kg/day PO divided q12hr for 10 days; not to exceed 500 mg/dose

Bronchitis

• <6 months: Safety and efficacy not established
• ≥6 months: 15 mg/kg/day PO divided q12hr for 10 days; not to exceed 500 mg/dose

Skin Infections

• <6 months: Safety and efficacy not established
• ≥6 months: 15 mg/kg/day PO divided q12hr for 10 days; not to exceed 250 mg/dose

Streptococcal Pharyngitis

• <6 months: Safety and efficacy not established
• ≥6 months: 7.5 mg/kg q12hr for 10 days; individual dose not to exceed 250 mg

Endocarditis (Off-label)

• 15 mg/kg PO 30-60 minutes before procedure; individual dose not to exceed 500 mg     

Pertussis (Off-label)

• <1 month: Safety and efficacy not established
• 1-6 months: 7.5 mg/kg/dose PO q12hr for 7 days

>6 months: 7.5 mg/kg/dose PO q12hr for 7 days

Paractamol

• Analgesic and antipyretics
• Not anti-inflammatory effect
• Suitable for Temperature between (37.5C – 38.5C)
• Safe under 6 months

Trade names  : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )

Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories, 1g/100ml solution for infusion

Dose : 

Tablet, capsule : 

• 500mg tabs 1-2 tabs /cap every 6 hours

Syrup, suspension :

• < 5year  : 125mg/5ml susp (w/2) Every 4 – 6 hours
• 5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours 

Suppositories :

• <1Y : 125 mg supp Every 8 hours  (1 supp x 3 )
• >1Y : 250mg supp Every 8 hours ( 1supp x 3 )

Iv solution 1g/100ml :

• <10kg : 0 .75ml/kg 
• >10kg , <50kg :  1.5ml/kg
• >50kg : 100ml Slowly over 15 minute

Maximum dose : 4g daily 

Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding

Brufen

• Analgesic and antipyretics
• Has anti-inflammatory effect
• Suitable for Temperature( 38-38.5) C
• Not save under 6 months
• Taken After meal
  • 200mg every 6-8 hours, May increase to 400mg every 6-8hours 

Trade names :  brufen (Taskine , Doloraz, Iburam,Remofen , Ibugesic, Sapofen, Perofen, Rupan,Bulkaprofen, Advil liquid-gel , Profast, Nashat ,Midofen, Ibusoft).

Other concentration: 800mg and 400mg tablet 600mg tablet, 100mg/5ml syrup

Dose:

Tablets :

Syrup, suspension :

• 100mg/5ml Syrup(Wx0.375) every 6-8hours

Oral drops :

40mg/1ml 

• 6-11 months  : 1.25ml every 8 hours
• 12-23months : 1.8ml every 8 hours

Maximum dose : 3200 mg per day  

Contraindication: 

• History of hypersensitivity to aspirin or other NSAIDs
• current or recent stomach ulcer
• severe heart failure.
• severe liver disease

Pregnancy : not usually recommended in pregnancy