1. Cephadroxil 500 mg capsule  1x2x10
2. Brufen 400mg tablet +  Paracetamol ( Revenin)500mg tablets  alternately every 4-6       hours until fever subside
3. Gurgle with salt and water solution (don’t swallow it ) 3 times daily
4. Soft food and warm drinks

Cephadroxil

Dosage Forms & Strengths:

• 500mg caps, 1g tab, 125mg /5ml suspension, 250mg /5ml suspension, 500mg/5ml suspension 

Trade names  :

• Droxicef , Biodroxil, Cefadroxil, Cefadroxil, Droxil, Cedrox, Cefadril, Duricef, Midroxil

Therapeutic indication and dose :

Pharyngitis

• 1 g PO qDay or divided q12hr for 10 days

Skin & Skin Structure Infections

• 1 g PO qDay or divided q12hr

Tonsillitis

• 1 g PO qDay or divided q12hr for 10 days

Urinary Tract Infections

• 2 g PO qDay or divided q12hr

Endocarditis

• Prophylaxis (dental, upper respiratory procedure): 2 g PO 1 hour before procedure

Contraindications:

• Hypersensitivity to cefadroxil and to any of the cephalosporins
• History of severe reactions to penicillins or to any other beta-lactam drug

Pregnancy: The safe use during pregnancy has not been established. 

Breast-feeding:

• Cefadroxil is present in low concentrations in breast milk
• Sensitization, diarrhea or colonization of the infants’ mucosa with fungi are possible. 
• The use of cefadroxil during pregnancy and in lactating mothers should therefore be handled very strictly. 

Side effect:

• Nausea, vomiting, diarrhoea, dyspepsia, abdominal pain, glossitis
• Pruritus, rash, allergic exanthema, urticaria. 

Paractamol

• Analgesic and antipyretics
• Not anti-inflammatory effect
• Suitable for Temperature between (37.5C – 38.5C)
• Safe under 6 months

Trade names  : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )

Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories, 1g/100ml solution for infusion

Dose : 

Tablet, capsule : 

• 500mg tabs 1-2 tabs /cap every 6 hours

Syrup, suspension :

• < 5year  : 125mg/5ml susp (w/2) Every 4 – 6 hours
• 5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours 

Suppositories :

• <1Y : 125 mg supp Every 8 hours  (1 supp x 3 )
• >1Y : 250mg supp Every 8 hours ( 1supp x 3 )

Iv solution 1g/100ml :

• <10kg : 0 .75ml/kg 
• >10kg , <50kg :  1.5ml/kg
• >50kg : 100ml Slowly over 15 minute

Maximum dose : 4g daily 

Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding

Brufen

• Analgesic and antipyretics
• Has anti-inflammatory effect
• Suitable for Temperature( 38-38.5) C
• Not save under 6 months
• Taken After meal
  • 200mg every 6-8 hours, May increase to 400mg every 6-8hours 

Trade names :  brufen (Taskine , Doloraz, Iburam,Remofen , Ibugesic, Sapofen, Perofen, Rupan,Bulkaprofen, Advil liquid-gel , Profast, Nashat ,Midofen, Ibusoft).

Other concentration: 800mg and 400mg tablet 600mg tablet, 100mg/5ml syrup

Dose:

Tablets :

Syrup, suspension :

• 100mg/5ml Syrup(Wx0.375) every 6-8hours

Oral drops :

40mg/1ml 

• 6-11 months  : 1.25ml every 8 hours
• 12-23months : 1.8ml every 8 hours

Maximum dose : 3200 mg per day  

Contraindication: 

• History of hypersensitivity to aspirin or other NSAIDs
• current or recent stomach ulcer
• severe heart failure.
• severe liver disease

Pregnancy : not usually recommended in pregnancy