- Cefuroxime 250mg tablet orally 1 x 2 x 10
- Inflaban 25 mg tablet 1×3 until fever subside
- Gurgle with salt and water solution (don’t swallow it ) 3 times daily
- Soft food and warm drinks
Cefuroxime
Dosage Forms & Strengths:
- 125 mg, 250mg, 500mg tablet, 125mg /5ml suspension, 250 mg/5ml suspension , 750mg 1500mg 250mg vial for iv injection
Trade names :
- Zinnat , U-cef ,Cefovex, Ceftal ,Zamur, Oraxim Daroxime, Medo-axitine,Cefutil, Zinoximor, Cefurex , Cefuzime, Furocef ,Maxil , Vaxcel cefuroxime, Xorim , Xorimax , Zilisten, Zinacef, Zinoxime
Therapeutic indication and dose :
Pharyngitis/Tonsillitis
- 250 mg PO q12hr for 10 days
Acute Bacterial Maxillary Sinusitis
- 250 mg PO q12hr for 10 days
Acute Bacterial Exacerbations of Chronic Bronchitis
- 250-500 mg PO q12hr for 10 days
- 500-750 mg IV q8hr; switch to oral therapy as soon as clinically possible
Secondary Bacterial Infections of Acute Bronchitis
- 250-500 mg PO q12hr for 5-10 days
Uncomplicated Pneumonia
- 750 mg IV/IM q8hr
Uncomplicated Skin/Skin Structure Infections
- 250-500 mg PO q12hr for 10 days
- 750 mg IV/IM q8hr; switch to oral therapy as soon as clinically possible
Uncomplicated Urinary Tract Infections
- 125-250 mg PO q12hr for 7-10 days
- 750 mg IV/IM q8hr; switch to oral therapy as soon as clinically possible
Gonorrhea
- Uncomplicated: 1 g PO once or 1.5 g IM once at 2 different sites with 1 g probenecid PO
- Disseminated: 750 mg IV/IM q8hr
Severe or Complicated Infections
- 1.5 g IV/IM q8hr; may be administered q6hr in life-threatening situations
Contraindications
- Hypersensitivity to cephalosporin antibiotics.
- History of severe hypersensitivity to any other type of betalactam antibacterial agent (penicillins, monobactams and carbapenems).
Pregnancy
- Cefuroxime axetil should be prescribed to pregnant women only if the benefit outweighs the risk.
- Category B
Breastfeeding
- Cefuroxime is excreted in human milk in small quantities. A risk of diarrhea and fungus infection of the mucous membranes cannot be excluded.
- Breastfeeding might have to be discontinued due to these effects, Cefuroxime should only be used during breastfeeding after benefit/risk assessment by the physician in charge.
Side effect:
- Candida overgrowth
- System disorders
- Eosinophilia
- Headache, dizziness
- Diarrhea, nausea, abdominal pain
Transient increases of hepatic enzyme levels
Diclofenac sodium
- Mainly analgesic
- Has anti-inflammatory effect
- Suitable for temperature >39
- Contraindicated in < 1year age
- After meal
Trade names of diclofenac : (Diclogesic, Votrex, Infla-ban, Voltaren, Tratul, Rofenac Diclofen, Olfen,Optifen, Almiral, Clofen, Diclosal, Divido, Diclomax, Nalgofen, Difen,)
Other concentrations: 12.5 mg, 50, 100 suppositories, 25, 50, 100 tablet, 100 capsules, 75 mg/3ml mg injection
Dose :
Tablet:
- 75 mg to 150 mg daily in two or three divided doses.
Suppositories :
Adults: 75-150mg daily, in divided doses every 12 hour
children:
- 1-3 years or <15 kg: 12.5 mg suppositories every 12 hour
- 3-12years or >15kg : 25mg suppositories every 12 hour
IM Injection 75mg/3ml
Adults : 25 to 75 mg depending on the severity pain.
The maximum daily dose is :150 mg.
Contraindication:
- History of hypersensitivity to diclofenac sodium
- Asthma
- Hypertension
- current or recent stomach ulcer
- severe heart failure.or evere liver disease
Pregnancy : not usually recommended in pregnancy
Give antipyretic:
Perflgan 1g/100ml intravenous injection :
Dose:
Pediatrics:
<10kg : 0 .75ml/kg
>10kg , <50kg : 1.5ml/kg
>50kg : 100ml Slowly over 15 minute
Adult:
100ml Slowly over 15 minute
OR
Diclofenac sodium injection 75 mg/3ml intramuscular injection :
Dose:
Pediatrics:
> 1year : 1ml/20kg every 12 hour .
Adult:
25 to 75 mg(1-3ml) depending on the severity pain.
If the pain still severe, you may decide to give a second injection after 6 hours.
Give Antibiotic:
Lincomycin 600mg/2ml
Dose:
Pediatrics:
IV: 10-20 mg/kg/day divided q8-12hr
IM: 10 mg/kg q12-24hr
Adult:
IM: 600 mg q12-24hr
IV: 600-1000 mg q8-12hr; not to exceed 8 g/day