1. Amoclan 625mg tablet 1 x 3 x 10 Or Amoclan  1g tablet 1 x 2 x 10
2. Voltaren 25 mg tablet + Paracetamol ( Revenin)500mg tablets  alternately every 6 hours until fever subside
3. Gurgle with salt and water solution (don’t swallow it ) 3 times daily
4. Soft food and warm drinks

Amoxicillin with clavulanic acid

Dosage Forms & Strengths:

• 375mg tablet, 625mg tablet, 1g tablet, 156mg/5ml suspension, 312mg /5ml suspension, 200mg/5ml suspension, 400mg/5ml suspension, 600mg/5ml suspension, 457 mg /5ml suspension, 62.5mg/5ml drops , 600 vial injection , 1200 vial injection .

Trade names  :

• Clavar , Klavox, Moxiclav, Ramoclav, Curam, Julmentin, Augmentin, Clavodar, Amoclan

Therapeutic indication and dose :

Lower Respiratory Tract Infection :

• Mild to moderate: 375mg  PO q8hr for 10 days
• Severe: 625 mg PO q8hr or 2000 mg (2 extended-release tabs) PO q12hr for 7-10 days

Chronic Obstructive Pulmonary Disease

• 625 mg PO q8hr

Acute Bacterial Sinusitis

• 2000 mg (2 extended-release tablets) PO q12hr for 10 days

Animal/Human Bite Wounds

• 625mg PO q8hr for 3-5 days

Erysipelas

• 625 mg PO q8hr for 7-10 days

Pyelonephritis

• 625mg PO q8hr

Skin Abscess

• 625 mg PO q12hr

Diabetic Foot

Mild to moderate, localized cellulitis

• 2000 mg (2 extended-release tablets) PO q12hr for 7-14 days

Group A Streptococci, Chronic Carrier

• 40 mg/kg/day PO divided q8hr for 10 days; not to exceed 2000 mg/day

Contraindications:

• Hypersensitivity to penicillin’s
• History of a severe immediate hypersensitivity reaction (e. g. Anaphylaxis) to another beta-lactam agent (e. g. A cephalosporin, carbapenem or monobactam). 
• Hepatic and renal impairment

Pregnancy:

• Category B

Breastfeeding :

• Both substances are excreted into breast milk, diarrhea and fungus infection of the mucous membranes are possible in the breast-fed infant, so that breast-feeding might have to be discontinued. 

Common side effects:

• Diarrhea, nausea and vomiting. 
• Mucocutaneous candidosis
• Skin rash, itching, hives
• Vaginal itching and discharge

Diclofenac sodium

• Mainly analgesic
• Has anti-inflammatory effect
• Suitable for temperature >39
• Contraindicated in < 1year age
• After meal

Trade names  of diclofenac  : (Diclogesic, Votrex, Infla-ban, Voltaren, Tratul, Rofenac Diclofen, Olfen,Optifen, Almiral, Clofen, Diclosal, Divido, Diclomax, Nalgofen, Difen,)

Other concentrations: 12.5 mg, 50, 100 suppositories, 25, 50, 100 tablet, 100 capsules, 75 mg/3ml mg injection

Dose : 

Tablet: 

• 75 mg to 150 mg daily in two or three divided doses. 

Suppositories :

Adults: 75-150mg daily, in divided doses every 12 hour

children:

• 1-3 years or <15 kg: 12.5 mg suppositories every 12 hour
• 3-12years or >15kg : 25mg suppositories every 12 hour

IM Injection 75mg/3ml

Adults :  25 to 75 mg depending on the severity pain. 

The maximum daily dose is :150 mg.

Contraindication: 

• History of hypersensitivity to diclofenac sodium
• Asthma 
• Hypertension
• current or recent stomach ulcer
• severe heart failure.or evere liver disease

Pregnancy : not usually recommended in pregnancy

Paractamol

• Analgesic and antipyretics
• Not anti-inflammatory effect
• Suitable for Temperature between (37.5C – 38.5C)
• Safe under 6 months

Trade names  : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )

Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories, 1g/100ml solution for infusion

Dose : 

Tablet, capsule : 

• 500mg tabs 1-2 tabs /cap every 6 hours

Syrup, suspension :

• < 5year  : 125mg/5ml susp (w/2) Every 4 – 6 hours
• 5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours 

Suppositories :

• <1Y : 125 mg supp Every 8 hours  (1 supp x 3 )
• >1Y : 250mg supp Every 8 hours ( 1supp x 3 )

Iv solution 1g/100ml :

• <10kg : 0 .75ml/kg 
• >10kg , <50kg :  1.5ml/kg
• >50kg : 100ml Slowly over 15 minute

Maximum dose : 4g daily 

Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding