Bacterial tonsillitis (3)
- Amoxicillin 125mg/5ml suspension (w*0.27) x 3×10-14 OR Amoxicillin 250mg/5ml suspension (wx0.13) x 3×10-14
- Brufen 100mg/5ml syrup (Wx0.375) + Paracetamol ( Revanin) 125mg/5ml Syrup (w/2) alternately every 6 hours until fever subside
Amoxicillin :
Ear, Nose, & Throat Infections
Mild to moderate infections
- >3 months and <40 kg: 20 mg/kg/day PO divided q8hr
Severe infections
- >3 months and <40 kg: 40 mg/kg/day PO divided q8hr
Acute Otitis Media
- ≥2 months and children: 80-90 mg/kg/day PO in divided doses q12hr
- Age <2 years or severe symptoms (any age): Standard 10-day course
- >2 years with mild or moderate AOM: 5-7-day course
Lower Respiratory Tract Infections
Mild, moderate, or severe infections
>3 months and <40 kg: 40 mg/kg/day PO divided q8hr
Pneumonia, community-acquired (Off-label)
≥3 months:
Immediate release
Empiric treatment: 90 mg/kg/day PO divided q12 hr for 10 days; not to exceed 4,000 mg/day
Group A Streptococcus: 50-75 mg/kg/day PO divided q12hr for 10 days; not to exceed 4,000 mg/day
H. influenza: 75-100 mg/kg/day PO divided q8hr for 10 days; not to exceed 4,000 mg/day
Infective Endocarditis (Off-label)
Prophylaxis
- 50 mg/kg PO 30-60 min before procedure
Paractamol
- Analgesic and antipyretics
- Not anti-inflammatory effect
- Suitable for Temperature between (37.5C – 38.5C)
- Safe under 6 months
Trade names : ( Revanin ,Adol,Panda,Dolocet ,Feverol, panadol )
Concentrations: 500 mg tablet, ,1g tablet ,125 mg/5 ml syrup, 250 mg/5 ml syrup, 125 mg suppositories, 250 mg suppositories, 1g/100ml solution for infusion
Dose :
Tablet, capsule :
- 500mg tabs 1-2 tabs /cap every 6 hours
Syrup, suspension :
- < 5year : 125mg/5ml susp (w/2) Every 4 – 6 hours
- 5-12 year : 250mg/5ml susp (w/4) Every 4 – 6 hours
Suppositories :
- <1Y : 125 mg supp Every 8 hours (1 supp x 3 )
- >1Y : 250mg supp Every 8 hours ( 1supp x 3 )
Iv solution 1g/100ml :
- <10kg : 0 .75ml/kg
- >10kg , <50kg : 1.5ml/kg
- >50kg : 100ml Slowly over 15 minute
Maximum dose : 4g daily
Pregnancy and lactation : Paracetamol is the first choice of painkiller in pregnancy and breastfeeding
Brufen
- Analgesic and antipyretics
- Has anti-inflammatory effect
- Suitable for Temperature( 38-38.5) C
- Not save under 6 months
- Taken After meal
- 200mg every 6-8 hours, May increase to 400mg every 6-8hours
Trade names : brufen (Taskine , Doloraz, Iburam,Remofen , Ibugesic, Sapofen, Perofen, Rupan,Bulkaprofen, Advil liquid-gel , Profast, Nashat ,Midofen, Ibusoft).
Other concentration: 800mg and 400mg tablet 600mg tablet, 100mg/5ml syrup
Dose:
Tablets :
Syrup, suspension :
- 100mg/5ml Syrup(Wx0.375) every 6-8hours
Oral drops :
40mg/1ml
- 6-11 months : 1.25ml every 8 hours
- 12-23months : 1.8ml every 8 hours
Maximum dose : 3200 mg per day
Contraindication:
- History of hypersensitivity to aspirin or other NSAIDs
- current or recent stomach ulcer
- severe heart failure.
- severe liver disease
Pregnancy : not usually recommended in pregnancy
Give antipyretic:
Perflgan 1g/100ml intravenous injection :
Dose:
Pediatrics:
<10kg : 0 .75ml/kg
>10kg , <50kg : 1.5ml/kg
>50kg : 100ml Slowly over 15 minute
Adult:
100ml Slowly over 15 minute
OR
Diclofenac sodium injection 75 mg/3ml intramuscular injection :
Dose:
Pediatrics:
> 1year : 1ml/20kg every 12 hour .
Adult:
25 to 75 mg(1-3ml) depending on the severity pain.
If the pain still severe, you may decide to give a second injection after 6 hours.
Give Antibiotic:
Lincomycin 600mg/2ml
Dose:
Pediatrics:
IV: 10-20 mg/kg/day divided q8-12hr
IM: 10 mg/kg q12-24hr
Adult:
IM: 600 mg q12-24hr
IV: 600-1000 mg q8-12hr; not to exceed 8 g/day